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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image27th July 2026 Vol. No. 15 ; Issue No.745
Publications

1. Chakraborty S, Shenoy PS, Nath S, Panda TR, Bhat A, Sakpal A, Mehrotra M, Singh P, Patra M, Ray P (2026). A kinetically inert platinum antitumor agent overcomes mutant p53-driven chemoresistance via oxidative stress-mediated DNA damage. Medical Oncology.;43(9):232.

2. Choudhari D, Chatterjee A, Gulia A, Salunkhe B (2026). Postoperative Pain Severity, Incidence of Chronic Pain, and Impact on Daily Function following Oncological Total Knee Replacements at Tertiary care centre. Indian Journal of Orthopaedics. 18;60(7):1684-1694.

3. Pruthi M, Reddy A, Gulia A, Nayak P, Panjwani P, Puri A (2026). Evaluation of the Prognostic and Therapeutic Factors Affecting Outcomes in Parosteal Osteosarcoma of Bone. Indian Journal of Orthopaedics.;60(7):1641-1653.

4. Priya RL, Poriwade S, Parthasarathy A, Movva SH, Shinde I, Redhu AK, Chandrani P, Gota V (2026). FloraMediX: AI-enabled recognition and therapeutic profiling analysis of indian medicinal flora. Frontiers in Bioinformatics. 6:1864201.

5. Singh S, Wang Y, Sircar A, Jindal U, Srour N, La Ferlita A, Distefano R, Soni A, Kumar D, Peralta-Camacho GJ, Zhao SL, Jafari H, Holter JC, Tinapple JW, Barlage JM, Kumar R, Berger M, Rahman K, Nezati R, Nath UK, Chaudhary N, Ranganathan P, Muthusamy N, Amador V, Li PK, Parekh S, Paik J, Baiocchi R, Song JW, Alinari L, Peterson BR, Epperla N, Jain N, Sehgal L (2026). Identifying the angiogenic receptor expression in mantle cell lymphoma patients and murine models. Biomarker Research. 14(1):84.

6. Gupta T, Dasgupta A, Chatterjee A, Chinnaswamy G (2026). Comment on: Group 4 Medulloblastomas of early childhood treated with high-dose chemotherapy- and craniospinal irradiation-Sparing approach-finding the right balance between survival and Survivorship. Pediatric Blood Cancer.

7. Agrawal R, Parghane RV, Joshi A, Prabhash K, Basu S (2026). Evaluation of [225Ac]Ac-PSMA-617 vis-a-vis Rechallenge [177Lu]Lu-PSMA-617 PRLT Versus cabazitaxel or oral metronomic chemotherapy in mCRPC: An observational analysis of outcome and toxicity profiles in a real-world clinical scenario. Prostate.

Site of the Week

The Immune Epitope Database (IEDB) is a freely available resource funded by NIAID. It catalogs experimental data on antibody and T cell epitopes studied in humans and other animal species in the context of infectious disease, allergy, autoimmunity and transplantation.

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Interesting Reads

Liu S, Peterson JF, Wright A (2026). How Generative AI Should Transform Clinical Decision Support. JAMA.

Video of the Week
From Screening to Precision Prevention: AI in Breast Cancer Detection and Care (ESIL)
Upcoming Events
IMPACT 2026 : Three Day Manuscript Writing Workshop

August 21-23, 2026

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

Workshop on Cancer Epidemiology and Public Health

September 3-5, 2026,

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

Cytogenomic Microarray Workshop

October 26-29, 2026.

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

Do You Know?

In 2012, Smart-seq, a method to generate high-coverage transcriptomes from single cells, was used to analyse the full-length messenger-RNA transcriptomes of circulating tumour cells from a patient with melanoma.

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Cancer News
New cancer strategy could stop tumors before resistance takes hold.

Sciencedaily, 22/07/2026

Researchers are applying evolutionary theory to cancer by changing treatments before tumors have time to develop resistance. Mathematical models suggest that rapid, carefully timed switches between multiple therapies could improve cure rates...

Transmissible cancer cells discovered in fish act more like parasites than traditional tumors.

Phys.org, 22/07/2026

Using whole-genome sequencing, the team compared DNA from tumors and healthy tissues in affected fish. They found that the cancer cells were much more closely related to each other than to their host fish—the signature of a clonally transmissible cancer...

Thymus-derived hormone may suppress age-related inflammation and boost cancer therapy.

MedicalXpress, 21/06/2026

Chronic inflammation can also interfere with the immune system's ability to attack tumors. In older mice with cancer, adding thymulin boosted the immune response against tumors and improved overall survival. Adding thymulin also made older mice more responsive to anti-PD-1/PD-L1 therapy...

2026 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)